Research Interests: Nuclear RNA processing and export is an essential task in all eukaryotes, but despite the vital significance of this process, many basic fundamental questions remain. These include: How does an RNA transit through a nuclear pore complex? How is RNA export altered in response to stress or viral infection? How do mutations in RNA export machinery contribute to disease? The Montpetit Lab is studying these cell biology questions with the goal of describing how components of nuclear pore complexes (NPC) direct and regulate RNA export at a cellular, molecular, and atomic level. Ultimately, this will allow us to better understand the interplay between nuclear RNA export, gene expression, and disease.