Disease-Causing Nibbling Amoeba Hides by Displaying Proteins From Host Cells

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A parasitic amoeba that causes severe gut disease in humans protects itself from attack by biting off pieces of host cells and putting their proteins on its own surface, according to a study by microbiologists at the University of California, Davis.

“We’re very excited about how this ties into amoebic infection and into broader themes in cell biology,” said Katherine Ralston, assistant professor in the Department of Microbiology and Molecular Genetics, College of Biological Sciences. A paper describing the work appears today in the journal mBio.

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