Research Interests: Mosquito-borne flaviviruses such as dengue virus and Zika virus are a source of emerging and re-emerging infectious diseases. We study how these viruses hijack host machinery through virus-host protein interactions to better understand their replication and develop therapeutics. We use complementary techniques of global proteomics, genetics, and high-throughput sequencing to tackle these questions.
Research Interests: We study host-parasite interactions between the intracellular parasite Toxoplasma gondii and its hosts. Toxoplasma can cause severe disease but its virulence differs, often quite dramatically, depending on the infecting strain and the host. Our focus is to identify genes of Toxoplasma that modulate the host cell and/or determine virulence, host genes and pathways that determine resistance/susceptibility, and to characterize their specific interactions.
Research Interests: Soil microbiology, biological regulation of biogeochemical cycles, microbial diversity, land use change, tropical forest conservation and ecology, C and N turnover in termite hindguts
Research Interests: Parasitology and host-pathogen interactions. Pathogenesis of Entamoeba histolytica infection. Host and amoeba cell biological pathways including phagocytosis, cytotoxicity, cell death and repair